ea0035p377 | Diabetes (epidemiology, pathophysiology) | ECE2014
Zaman Iftikhar
, Swaminathan Ramasamyiyer
, Brackenridge Anna
, Sankaralingam Arun
, McGowan Barbara
Introduction: Gestational diabetes mellitus (GDM) is an important co-morbidity of pregnancy, with insulin resistance a key contributor in its underlying pathology. Relaxin is a hormone considered crucial for mediating adaptations deemed vital for maintenance of pregnancy. Evidence has suggested that levels of plasma relaxin may be positively correlated with insulin sensitivity. This led us to hypothesize that relaxin may play a role in the pathogenesis of insulin resistance in...